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1 article(s) from Rentmeister, Andrea

Synthetic mRNA capping

Fabian Muttach,
Nils Muthmann and
Andrea Rentmeister

Beilstein J. Org. Chem. 2017, 13, 2819–2832, doi:10.3762/bjoc.13.274

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Graphical Abstract

Figure 1: Schematic representation of enzymatic 5′-cap formation in eukaryotic mRNA. The 5′-triphosphate-end ...

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Figure 2: Nucleotide analogues 1–11 were converted by Paramecium bursaria Chlorella virus-1 capping enzyme in...

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Figure 3: Schematic representation of co-transcriptional capping with different cap analogues. A DNA-dependen...

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Figure 4: (A) Structures of commercially available mRNA cap analogues. (B) Synthetic route to cap analogues a...

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Figure 5: Enzymatic modification of cap analogues at their N²- or N7-position or a combination of both. (A) F...

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Figure 6: Synthesis of cap-containing RNA by solid-phase synthesis. (A) A TMG-capped mRNA was synthesized sta...

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Figure 7: Click chemistry for the preparation of capped RNA and cap analogues. (A) Preparation of capped RNA ...

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Review

Published 20 Dec 2017

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